ANTIMICROBIAL RESISTANCE SOLUTIONS
WITH DR. JOHN H. REX
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R&D Insight
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Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics. And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.
Dame Sally Davies Tweet
New pipeline analysis: Cancer projects were funded 17x more than antibacterials during 2011-2020
Developing antibiotics for children: There are no easy answers
What does an antibiotic cost to develop? What is it worth? How to afford it?
FDA Workshop: Animal Models To Support Antibacterial Development (5 Mar 2020, post-meeting notes)
The 6 meanings of “Lack of Access” (UNSLAP)
How hard (and how) to Pull? Net value of Pull via a Transferrable Exclusivity Extension (TEE)
IDSA White Paper on developing narrow-spectrum antimicrobials + editorial by G. Drusano
FDA analysis of 40-years of antibacterial development: Dheman et al.
New mechanisms for antibiotic reimbursement in the United States: CMS’s IPPS FY2020 Final Rule
NIAID workshop: What is a robust PK-PD package?
Lessons in Discovery from Lynn Silver + Pro-con on alternatives to antibiotics
Push! Pull! Push! Pull! / Highlights from Davos 2018
The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.
Alexander Fleming Tweet
The bipartisan PASTEUR Act is the strongest bill ever written to strengthen antibiotic development and use. It will fix our market failures, expand the pipeline for next generation antibiotics, and save lives. We can’t sit on our hands as this public health crisis arrives – we have to act now.
U.S. Senator Michael Bennet Tweet